Related Experiment Video
Updated: Jun 4, 2026
BrainBeats as an Open-Source EEGLAB Plugin to Jointly Analyze EEG and Cardiovascular Signals
Published on: April 26, 2024
Normalized spectral power of fetal heart rate variability is associated with fetal scalp blood pH
J O E H van Laar1, C H L Peters, S Houterman
1Department of Obstetrics and Gynaecology, Máxima Medical Centre, Veldhoven, The Netherlands. joehvanlaar@hotmail.com
Background:
Spectral power of fetal heart rate variability is related to fetal condition. Previous studies found an increased normalized low frequency power in case of severe fetal acidosis.
Aims:
To analyze whether absolute or normalized low or high frequency power of fetal heart rate variability is associated with fetal scalp blood pH.
Study Design:
Prospective cohort study, performed in an obstetric unit of a tertiary care teaching hospital.
Subjects:
Consecutive singleton term fetuses in cephalic presentation that underwent one or more scalp blood samples, monitored during labour using ST-analysis of the fetal electrocardiogram. Ten-minute continuous beat-to-beat fetal heart rate segments, preceding the scalp blood measurement were used.
Outcome Measures:
Absolute and normalized spectral power in the low frequency band (0.04-0.15 Hz) and in the high frequency band (0.4-1.5 Hz).
Results:
In total 39 fetal blood samples from 30 patients were studied. We found that normalized low frequency and normalized high frequency power of fetal heart rate variability is associated with fetal scalp blood pH. The estimated ß of normalized low frequency power was -0.37 (95% confidence interval -0.68 to -0.06) and the relative risk was 0.69 (95% confidence interval 0.51-0.94). The estimated ß of normalized high frequency power was 0.33 (95% confidence interval 0.01-0.65) and the relative risk was 1.39 (95% confidence interval 1.01-1.92).
Conclusions:
Normalized low and normalized high frequency power of fetal heart rate variability is associated with fetal scalp blood pH.
