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Non-Destructive Evaluation of Regional Cell Density Within Tumor Aggregates Following Drug Treatment
Published on: June 21, 2022
The effect of local breast radiotherapy on circulating CD34(+) cells
Nehad M Alajez1, Wei Wang, Debashis Biswas
1Ontario Cancer Institute, Toronto, Canada.
Abstract:
The number of circulating CD34(+) (hematopoietic stem) cells (HSCs) was observed to decline by 15% in breast cancer patients after starting adjuvant radiation therapy, regardless of age or preceding chemotherapy. These data demonstrate that local radiation therapy can profoundly affect HSC homeostasis, which might have a myriad of important implications.
