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Updated: Jun 4, 2026

Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
Silent sinus syndrome: a rare presentation after botulinum toxin injection
Kimberly A Singh1, W Byron Barber, Mark A Codner
1Emory University School of Medicine, Division of Plastic and Reconstructive Surgery, Atlanta, GA 30318, USA.
Abstract:
Silent sinus syndrome is a unique diagnosis characterized by spontaneous enophthalmos and hypoglobus resulting from collapse of the orbital floor secondary to chronic subclinical sinusitis. Although reported in the ophthalmology and otolaryngology literature, there is no mention of silent sinus syndrome in the plastic surgery literature. The authors present a case report, along with a brief overview of silent sinus syndrome, so that knowledge of this rare but potentially devastating clinical entity may supplement plastic surgeons' differential to ensure proper diagnosis and treatment.
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