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Updated: Jun 4, 2026
Harnessing the Bioorthogonal Inverse Electron Demand Diels-Alder Cycloaddition for Pretargeted PET Imaging
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Practical considerations in the exploitation of passive tumor targeting
1Department of Clinical Oncology, Derbyshire Royal Infirmary, Derby, UK.
Abstract:
Specific targeting of radioisotopes or toxic drugs to tumors for cancer detection and treatment is an enticing but elusive goal. It has proved difficult to achieve adequate concentration ratios between tumor and normal tissues to improve on standard diagnostic and therapeutic methods.
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