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Updated: Jun 4, 2026

Systematic Scoring Analysis for Intestinal Inflammation in a Murine Dextran Sodium Sulfate-Induced Colitis Model
Published on: February 14, 2021
[Complex procedure for diagnosis of manifestations in intestinal dysbacteriosis]
Abstract:
The procedure for diagnosing the degree of intestinal dysbacteriosis comprises a study of changes in the species-specific and quantitative composition of the intestinal microflora and additional determination via enzyme immunoassay of the levels of various classes of gram-negative endobacterial lipopolysacharide immunoglobulins in human coprofiltrates. Antiendotoxic antibody titers were in the range between 1:100 to 1:150; 1:200 to 1:400, and above 1:400 in the examinees with grades 1, 2, and 3 dysbacteriosis, respectively. The complex procedure for diagnosing the degree of intestinal dysbacteriosis is easy-to-use, has no expensive components, and enables a judgment of the degree of local antiendotoxin immunity in the intestine throughout the working day, which may be used for timely and individual correction.
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