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Updated: Jun 4, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Xanthane sesquiterpenoids: structure, synthesis and biological activity.
1Department of Pharmacognosy, University of Szeged, Szeged Eötvös u. 6, H-6720, Hungary. hohmann@pharm.u-szeged.hu.
This review surveys naturally occurring xanthanes and xanthanolides, detailing their structures, biological activities, and synthesis. It summarizes 112 compounds from 126 references, filling a gap in comprehensive literature on these natural products.
Area of Science:
- Natural Product Chemistry
- Organic Chemistry
- Pharmacognosy
Background:
- Xanthanes and xanthanolides are natural products with diverse biological activities.
- A comprehensive review on these compounds is currently lacking in the scientific literature.
Purpose of the Study:
- To provide a comprehensive survey of naturally occurring xanthanes and xanthanolides.
- To detail their chemical structures, biological activities, structure-activity relationships, and synthetic pathways.
Main Methods:
- Literature search and compilation of existing data on xanthanes and xanthanolides.
- Systematic summarization of information from 126 references.
- Analysis of structural features and biological properties of 112 identified compounds.
Main Results:
- Identification and summarization of 112 naturally occurring xanthanes and xanthanolides.
- Detailed description of their chemical structures and diverse biological activities.
- Exploration of structure-activity relationships and synthetic approaches.
Conclusions:
- This review consolidates existing knowledge on xanthanes and xanthanolides.
- It serves as a valuable resource for researchers in natural product chemistry and drug discovery.
- Highlights the need for further research into the synthesis and applications of these compounds.
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