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Updated: Jun 4, 2026

A Cognitive Paradigm to Investigate Interference in Working Memory by Distractions and Interruptions
Published on: July 16, 2015
Disorders of cognition
1Department of Neurology, Mayo Clinic College of Medicine, Scottsdale, AZ 85259, USA. woodruff.bryan@mayo.edu
Abstract:
Cognitive complaints are common in any adult neurology practice, and may present in a variety of ways other than classic "memory loss." In this article, the author reviews a simple approach to a symptom-based differential diagnosis, including recognition of impairment in several key cognitive domains as well as associated symptoms such as motor disorders, psychosis, and sleep disturbance. Standard evaluation and management strategies of the most common presentations of cognitive decline in an outpatient setting are reviewed.
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