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Updated: Jun 4, 2026
Three-dimensional Inflammatory Human Tissue Equivalents of Gingiva
Published on: April 3, 2018
[Giant cell granuloma outside the jaw three cases and literature review]
Shimin Li1, Shuyi Wang, Li Zhu
1Department of Pathology, EENT Hospital of Fudan University, Shanghai, 200031, China. lishimin@163.com
Objective:
To investigate the clinicopathological features, diagnosis and treatment of giant cell granuloma outside the jaw.
Method:
The clinical and pathological datas of 3 cases in nasopharynx, temporal bone and maxillary sinus were analyzed retrospectively. The relevant literatures were also reviewed.
Result:
The patients presented with local painless mass, part of which were aggressive. Histopathological feature was, replacement of the normal bone structure with proliferating fibrous tissue containing numerous giant cells was shown.
Conclusion:
Giant cell granuloma outside the jaw was a non-neoplastic lesion, and extremely rare. It was somewhat difficult to make a correct diagnosis. Combining the clinical data and pathological feature were more helpful to the diagnosis. Total surgical resection was an effective therapeutic method.
