Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Life Histories01:29

Life Histories

Constrained by limited energy and resources, organisms must compromise between offspring quantity and parental investment. This trade-off is represented by two primary reproductive strategies; K-strategists produce few offspring but provide substantial parental support, whereas r-strategists produce much progeny that receives little care. These strategies are related to an organism’s survival likelihood across its lifespan, which is represented by a survivorship curve. Three general types of...
Clot Retraction and Fibrinolysis01:16

Clot Retraction and Fibrinolysis

After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.
Microtubule Instability02:17

Microtubule Instability

Microtubules are hollow cylindrical filaments having a diameter of approximately 25 nm and a length that varies from 200 nm to 25 μm. GTP-bound tubulin subunits form αβ-heterodimers for microtubule assembly. These core building blocks interact longitudinally, polymerizing into protofilaments. The protofilaments then interact with one another through lateral bonding forces to form stable cylindrical microtubules. These cylindrical filaments are dynamic as they undergo repeated assembly and...
Conformations of Butane02:20

Conformations of Butane

Unlike ethane and propane that have only two major conformations, butane has more than two conformers. The staggered form of butane in which the bulky methyl groups on the two carbons are placed on opposite sides, that is, at a dihedral angle of 180°, is the lowest energy, most stable form — called the anti conformer. This conformation is stabilized due to the absence of steric repulsion between the largely spaced out methyl groups. The other two staggered conformations are degenerate and have...
π Molecular Orbitals of 1,3-Butadiene01:24

π Molecular Orbitals of 1,3-Butadiene

Conjugated dienes have lower heats of hydrogenation than cumulated and isolated dienes, making them more stable. The enhanced stabilization of conjugated systems can be understood from their π molecular orbitals.
The simplest conjugated diene is 1,3-butadiene: a four-carbon system where each carbon is sp2-hybridized and has an unhybridized p orbital that contains an unpaired electron. According to molecular orbital theory, atomic orbitals combine to form molecular orbitals such that the number...
Free-falling Bodies: Introduction01:07

Free-falling Bodies: Introduction

All objects, neglecting air resistance, fall with the same acceleration towards the Earth's center due to the force exerted by the Earth's gravity. This experimentally determined fact is unexpected because we are so accustomed to the effects of air resistance and friction that we expect light objects to fall slower than heavier ones. People believed that a heavier object had a greater acceleration when falling until Galileo Galilei (1564–1642) proved otherwise. We now know this is not the case.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Polypoid Acral Amelanotic Melanoma: A Rare Variant Treated with Wide and Deep Surgical Excision.

Acta dermatovenerologica Croatica : ADC·2026
Same author

Alopecia areata: current concepts.

Wiener klinische Wochenschrift·2026
Same author

Acral acanthotic anomaly: a comprehensive review.

Italian journal of dermatology and venereology·2026
Same author

Vincent A. Cipollaro MD (1931-2025): A Foundational Pillar in International Dermatology.

International journal of dermatology·2026
Same author

Cutaneous Amyloidosis: An Updated Approach Focusing on Macular Amyloidosis.

Dermatology (Basel, Switzerland)·2026
Same author

Keratin-TMAO dressing accelerates full-thickness skin wound healing in diabetic rats via M2-macrophage polarization and the activation of PI3K/AKT/mTOR signaling pathway.

International journal of biological macromolecules·2025

Related Experiment Video

Updated: Jun 4, 2026

Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes
03:53

Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes

Published on: April 19, 2024

Jean-Claude Bystryn 1938-2010. An obituary.

Sergei A Grando1, Karl Holubar, Robert A Schwartz

  • 1Department of Dermatology, University, California, Irvine, NJ, USA. sgrando@uci.edu

Experimental Dermatology
|February 18, 2011
PubMed
Summary
This summary is machine-generated.

Dr. Jean-Claude Bystryn pioneered research in autoimmune blistering diseases, melanoma, and alopecia areata. His work significantly advanced understanding of pemphigus mechanisms and treatment.

More Related Videos

Neutrophil Lifespan Extension with CLON-G and an In Vitro Spontaneous Death Assay
05:52

Neutrophil Lifespan Extension with CLON-G and an In Vitro Spontaneous Death Assay

Published on: May 12, 2023

An Innovative 3D-Printed Insert Designed to Enable Straightforward 2D and 3D Cell Cultures
08:17

An Innovative 3D-Printed Insert Designed to Enable Straightforward 2D and 3D Cell Cultures

Published on: January 6, 2023

Related Experiment Videos

Last Updated: Jun 4, 2026

Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes
03:53

Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes

Published on: April 19, 2024

Neutrophil Lifespan Extension with CLON-G and an In Vitro Spontaneous Death Assay
05:52

Neutrophil Lifespan Extension with CLON-G and an In Vitro Spontaneous Death Assay

Published on: May 12, 2023

An Innovative 3D-Printed Insert Designed to Enable Straightforward 2D and 3D Cell Cultures
08:17

An Innovative 3D-Printed Insert Designed to Enable Straightforward 2D and 3D Cell Cultures

Published on: January 6, 2023

Area of Science:

  • Dermatology
  • Autoimmune Diseases
  • Oncology

Background:

  • Dr. Bystryn was a renowned physician-scientist with global recognition.
  • His research focused on autoimmune blistering diseases, melanoma, and alopecia areata.

Discussion:

  • His most significant contribution was elucidating the mechanisms of acantholysis in pemphigus.
  • This research advanced the development of effective treatments for pemphigus.

Key Insights:

  • Innovative work on autoimmune blistering diseases, particularly pemphigus.
  • Significant contributions to understanding melanoma and alopecia areata.

Outlook:

  • Dr. Bystryn's legacy includes advancements in dermatologic conditions and patient care.
  • His scientific contributions will be long remembered by patients and colleagues.