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Impact of submucous myoma on the severity of anemia
Jehn-Hsiahn Yang1, Mei-Jou Chen, Chin-Der Chen
1Department of Obstetrics and Gynecology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Objective:
To analyze the impact of the diameter (myoma-φ) and the uterine cavity protruding proportion (protruding %) of the submucous myoma on serum hemoglobin (Hb) level.
Design:
Retrospective descriptive study.
Setting:
Tertiary university hospital.
Patient(S):
Two hundred fifty-nine women with a single submucous myoma.
Intervention(S):
Transvaginal ultrasound examination and office hysteroscopy.
Main Outcome Measure(S):
Myoma-φ and protruding % were determined with transvaginal ultrasound scan and office hysteroscopy. Menorrhagic period (months) and serum Hb were recorded within 2 weeks of these examinations.
Result(S):
Serum Hb negatively correlated with myoma-φ, protruding %, and menorrhagic period. The negative association between serum Hb and protruding % was even more prominent after adjusting for myoma-φ. Multivariate regression analysis revealed that myoma-φ and protruding %, after adjusting for the confounding effect of menorrhagic period, maintained a strongly negative correlation with serum Hb level. When myoma-φ was <2 cm, however, the serum Hb levels were similar regardless of the protruding %.
Conclusion(S):
For women with a single submucous myoma, myoma-φ and protruding % can determine the serum Hb level significantly . As myoma-φ and protruding % increased, the serum Hb level decreased accordingly.
