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Isolation, Characterization, And High Throughput Extracellular Flux Analysis of Mouse Primary Renal Tubular Epithelial Cells
Published on: June 20, 2018
Life-threatening hypokalaemic paralysis associated with distal renal tubular acidosis
M Vendeloo1, A L H J Aarnoudse, E F H van Bommel
1Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, the Netherlands. m.vendeloo@asz.nl
Abstract:
A 56-year-old woman developed acute respiratory failure requiring mechanical ventilation due to acute hypokalaemic paralysis. There was no gastrointestinal potassium loss nor was she taking diuretics. Additional analyses revealed a normal anion gap metabolic acidosis with a positive urine anion gap. An acid-load test revealed a renal urine acidification defect, leading to the diagnosis of distal renal tubular acidosis. Normalisation of serum potassium level was established with oral bicarbonate supplementation and temporary potassium supplementation.
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