Related Experiment Video
Updated: Jun 4, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
Arterial interventions for renovascular hypertension
Shams Iqbal1, Ashish Sharma, Stephan T Wicky
1Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Renovascular hypertension, often caused by renal artery stenosis, can be effectively treated with percutaneous intervention like angioplasty and stenting, especially in carefully selected patients.
Area of Science:
- Cardiology
- Nephrology
- Interventional Radiology
Background:
- Renovascular hypertension is a significant cause of secondary hypertension, frequently affecting younger individuals.
- The primary underlying pathology is renal artery stenosis, most commonly due to atherosclerosis (90%) and fibromuscular dysplasia.
- Both atherosclerosis and fibromuscular dysplasia are treatable with percutaneous interventional therapies.
Purpose of the Study:
- To review the role of percutaneous intervention in managing renovascular hypertension.
- To discuss the techniques of renal angioplasty and stenting for this condition.
Main Methods:
- Review of current literature on percutaneous interventions for renal artery stenosis.
- Analysis of outcomes for renal angioplasty and stenting in well-selected patients.
Main Results:
- Percutaneous intervention, including renal angioplasty and stenting, offers good outcomes in appropriately selected patients.
- Advances in medical therapies have improved blood pressure control, complementing interventional procedures.
Conclusions:
- Percutaneous intervention is a valuable treatment option for renovascular hypertension caused by renal artery stenosis.
- Renal angioplasty and stenting are key techniques in the interventional management of this condition.
Related Concept Videos
Antihypertensive Drugs: Direct Renin Inhibitors
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Antihypertensive Drugs: Angiotensin-Converting Enzyme Inhibitors
Antihypertensive Drugs: Angiotensin II Receptor Blockers
Antihypertensive Drugs: Vasodilators
Hypertension IV: Drug Therapy and Lifestyle Modifications

