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Erythrocyte superoxide dismutase activity in patients with pernicious anemia and chronic lymphocytic leukemia
A Stoklasová1, Z Randová, D Radochová
1Department of Biochemistry, Faculty of Medicine, Charles University, Hradec Králové.
Abstract:
Superoxide dismutase activity was determined in the erythrocytes of healthy individuals and patients suffering from pernicious anemia, chronic lymphocytic leukemia and dyserythropoetic anemia type II. Enzyme activity was significantly decreased in the group of patients with chronic lymphocytic leukemia treated with cytostatic drugs. Most pronounced decreased occurred in erythrocytes of patients with dyserythropoetic anemia.