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Updated: Jun 4, 2026

The Dyspepsia Educational Tool As a Novel Aid in Dyspepsia Management
Published on: June 29, 2019
WITHDRAWN: Psychological interventions for non-ulcer dyspepsia
Shelly Soo1, Paul Moayyedi, Jonathan J Deeks
1Department of Medicine/Gastroenterology, South Tyneside District Hosiptal, Harton Lane, South Shields, UK, NE34 0PL.
Psychological interventions may help non-ulcer dyspepsia (NUD) symptoms for up to a year, but evidence is limited. More research is needed to confirm the effectiveness of these treatments for NUD patients.
Area of Science:
- Gastroenterology
- Psychiatry
- Evidence-based Medicine
Background:
- Non-ulcer dyspepsia (NUD) patients often exhibit higher psychological distress, including anxiety and depression.
- The efficacy of psychological interventions for NUD remains uncertain.
Purpose of the Study:
- To review the effectiveness of various psychological interventions for NUD.
- To assess improvements in dyspepsia symptom scores and quality of life.
Main Methods:
- Systematic review of randomized controlled trials (RCTs) and quasi-RCTs.
- Searched multiple databases (Cochrane, MEDLINE, EMBASE, PsycLIT, CINAHL) and contacted experts.
- Included interventions: psychotherapy, psychodrama, CBT, relaxation therapy, hypnosis.
Main Results:
- Only four trials were identified, with diverse interventions and limited data synthesis.
- All trials suggested short-term benefits for dyspepsia symptoms, persisting for one year.
- Methodological concerns included small sample sizes and unadjusted statistical significance.
Conclusions:
- Insufficient evidence exists to confirm the efficacy of psychological interventions for NUD.
- Further high-quality RCTs are required to establish definitive conclusions.
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