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Updated: Jun 4, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Reactivity of a platinum-substituted borirene
Holger Braunschweig1, Qing Ye, Krzystof Radacki
1Institut für Anorganische Chemie, Julius-Maximilians-Universität Würzburg, Am Hubland, D-97074, Würzburg, Germany. h.braunschweig@mail.uni-wuerzburg.de
Abstract:
We report on (i) the reactivity of the title compound trans-[Cl(PMe(3))(2)Pt{μ-BN(SiMe(3))(2)C=C}Ph] (1), which underwent a photochemical rearrangement reaction to afford the platinum boryl complex trans-[Cl(PMe(3))(2)PtBN(SiMe(3))(2)C≡CPh] (2), (ii) a ring-opening reaction by chemoselective boron-carbon bond cleavage resulting in the amino(vinyl)borane trans-[Cl(PMe(3))(2)PtCH=C(BClN(SiMe(3))(2))Ph] (3), and (iii) a Cl-Br ligand exchange on the platinum atom yielding the Br-derivate trans-[Br(PMe(3))(2)Pt{μ-BN(SiMe(3))(2)C=C}Ph] (4). All compounds were fully characterized by multinuclear NMR spectroscopy and single crystal X-ray diffraction analysis.
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