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Updated: Jun 4, 2026

Analysis of Simian Immunodeficiency Virus-specific CD8+ T-cells in Rhesus Macaques by Peptide-MHC-I Tetramer Staining
Published on: December 23, 2016
Severe thrombocytopenia in aged rhesus macaques (Macaca mulatta) infected with simian varicella virus
Lisa C Halliday1, Jeffrey D Fortman
1Biologic Resources Laboratory, University of Illinois at Chicago, Chicago, Illinois, USA. lhall@uic.edu
Abstract:
Simian varicella virus was diagnosed in 2 geriatric rhesus macaques (Macaca mulatta). The macaques presented with typical skin lesions as well as severe thrombocytopenia as a result of infection. Idiopathic thrombocytopenic purpura is a known complication of varicella zoster virus infection in humans; however, this condition has not been reported previously as a complication of SVV infection. This case report discusses the clinical presentation, pathology, and thrombocytopenia of the affected macaques.

