[Thrombosis and assisted reproductive techniques (ART)].

Area of Science:

• Reproductive Medicine
• Vascular Medicine
• Thrombosis Research

Context:

• Assisted reproductive techniques (ART) usage has significantly increased globally.
• ART procedures include artificial insemination, in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), and embryo transfers.
• ART can be associated with severe ovarian hyperstimulation syndrome (OHSS).

Purpose:

• To provide an updated review of ART-associated thromboses.
• To discuss the prevention and treatment guidelines for ART-associated thromboses.
• To highlight the potential risks and complications of ART procedures.

Summary:

• Venous or arterial thrombosis is a rare but serious complication of ART, often occurring in unusual sites like head and neck vessels.
• The exact mechanism of ART-associated thrombosis remains unclear, though hypotheses exist.
• Thromboses are particularly concerning when they occur during pregnancy following ART.

Impact:

• This review aims to reduce the risk of thrombosis by suggesting preventive measures against OHSS and identifying high-risk individuals.
• Early detection of women at risk for OHSS and thrombosis is crucial for effective management.
• Potential thromboprophylaxis administration, though requiring further research for optimal timing and dosage, may mitigate risks.