Successful ECT treatment for medically refractory nonconvulsive status epilepticus in pediatric patient
Hae W Shin1, Cormac A O'Donovan, Jane G Boggs
1Department of Neurology, Wake Forest University North Carolina Baptist Hospital, Winston-Salem, NC, USA. hshin7507@gmail.com
Insights
Electroconvulsive therapy (ECT) offers a successful treatment for medically refractory nonconvulsive status epilepticus (NCSE) in pediatric patients. This approach was effective even without fully discontinuing antiepileptic drugs (AEDs).
Area of Science:
- Neurology
- Pediatric Neurology
- Epileptology
Background:
- Status epilepticus (SE) is a critical neurological emergency with high mortality, especially in refractory cases.
- Limited consensus exists for third and fourth-line treatments in refractory SE.
- Electroconvulsive therapy (ECT) is an established treatment for refractory epilepsy and SE, but its pediatric use is infrequent.
Observation:
- A 7-year-old pediatric patient presented with medically refractory nonconvulsive status epilepticus (NCSE).
- Conventional antiepileptic drug (AED) therapies were insufficient.
- ECT was considered as a subsequent treatment option.
Findings:
- Electroconvulsive therapy (ECT) was successfully administered to treat the pediatric patient's refractory NCSE.
- The treatment was effective without requiring complete withdrawal of existing antiepileptic drugs (AEDs).
- This case demonstrates the successful application of ECT in a challenging pediatric neurological condition.
Implications:
- ECT can be a viable and effective therapeutic option for pediatric nonconvulsive status epilepticus (NCSE) that is resistant to standard treatments.
- This case expands the understanding of ECT's utility in pediatric neurology.
- Further research into ECT protocols for pediatric refractory SE and NCSE is warranted.
Abstract:
Status epilepticus is a life threatening condition with a high mortality rate in spite of aggressive treatment. There is little consensus on third and fourth line approaches in refractory cases. While electroconvulsive therapy (ECT) has been employed successfully as a treatment for refractory epilepsy and status epilepticus (SE) after exhausting conventional therapy, its use for pediatric patients is limited. We describe a 7-year-old pediatric case in which ECT was used successfully to treat medically refractory nonconvulsive status epilepticus (NCSE) without complete withdrawal of antiepileptic drugs (AED).
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