Related Experiment Video
Updated: Jan 19, 2026
Quantitative Analysis of the Cellular Lipidome of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry
Published on: March 8, 2020
Determination of 14 monoalkyl phosphates, dialkyl phosphates and dialkyl thiophosphates by LC-MS/MS in human urinary
Thorsten Reemtsma1, Jana Lingott, Stefanie Roegler
1Technical University of Berlin, Department of Water Quality Control, Sekr KF 4, Strasse des 17 Juni 135, 10623 Berlin, Germany. thorsten.reemtsma@ufz.de
Abstract:
Human urine was analyzed for nine dialkyl (DAP) and five monoalkyl phosphates (MAP) by LC-MS/MS. Some phosphoric acid esters are industrial chemicals and other hydrolysis products of trialkyl or triaryl phosphates, used as pesticides, flame retardants or plasticizers. Five MAP and two DAP were detected here for the first time in human urine. Monobutyl, diethyl, diphenyl and diethylhexyl phosphate were determined with median concentrations in the μg/L-range. The total urinary concentration of the 14 DAP and MAP summed up to a median of 20μg/L. Inclusion of MAP in future biomonitoring studies should provide a more comprehensive picture of the exposure of humans to organophosphorus compounds.
