Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Acute Pancreatitis II: Pathophysiology01:21

Acute Pancreatitis II: Pathophysiology

The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recognizing malnutrition in adults with critical illness: Guidance statements from the Global Leadership Initiative on Malnutrition.

Clinical nutrition (Edinburgh, Scotland)·2025
Same author

Recognizing malnutrition in adults with critical illness: Guidance statements from the Global Leadership Initiative on Malnutrition.

JPEN. Journal of parenteral and enteral nutrition·2025
Same author

Protocol for a prospective cohort study on the use of clinical nutrition and assessment of long-term clinical and functional outcomes in critically ill adult patients.

Clinical nutrition ESPEN·2021
Same author

Fluid resuscitation after severe trauma injury : U-shaped associations between tetrastarch dose and survival time or frequency of acute kidney failure.

Medizinische Klinik, Intensivmedizin und Notfallmedizin·2019
Same author

[Erratum to: Quality of dying processes after commencement of the German Living Will Act : Experiences of a surgical intensive care unit].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2017
Same author

[Quality of dying processes after commencement of the German Living Will Act : Experiences of a surgical intensive care unit].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2016
Same journal

[Treatment of Vocal Fold Paralysis].

Zentralblatt fur Chirurgie·2026
Same journal

Zentralblatt fur Chirurgie·2026
Same journal

Predictive Factors for Mediastinal Lymph Node Metastases in Patients with Non-small Cell Lung Cancer, as Detected by Video-assisted Mediastinoscopic Lymphadenectomy.

Zentralblatt fur Chirurgie·2026
Same journal

[Robotic Management of a Bile Leak After Cholecystectomy Caused by an Aberrant Bile Duct of the Hepatic Segments, Using a Combined Biliodigestive Anastomosis Incorporating the Cystic Duct Stump].

Zentralblatt fur Chirurgie·2026
Same journal

[Microvascular Reconstruction of the Laryngotracheal Junction].

Zentralblatt fur Chirurgie·2026
Same journal

[Evaluation of Multimodal Perioperative Care Pathway Supported by a Patient-facing Mobile App in Colorectal Surgery - First Clinical Experience and Patient Satisfaction].

Zentralblatt fur Chirurgie·2026
See all related articles

Related Experiment Video

Updated: Jun 4, 2026

Retroperitoneal Laparoscopic Debridement and Drainage for Pancreatic Abscess
03:42

Retroperitoneal Laparoscopic Debridement and Drainage for Pancreatic Abscess

Published on: March 15, 2024

[Secondary peritonitis].

W Hartl1, D Kuppinger, M Vilsmaier

  • 1Chirurgische Klinik, Universität Campus Großhadern LMU München, München, Deutschland. whartl@med.uni-muenchen.de

Zentralblatt Fur Chirurgie
|February 22, 2011
PubMed
Summary
This summary is machine-generated.

Optimal surgical and antibiotic therapy are crucial for secondary peritonitis and organ failure. Achieving source control is the most critical factor for patient survival, with recent advances improving outcomes.

More Related Videos

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
06:45

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis

Published on: December 18, 2010

Related Experiment Videos

Last Updated: Jun 4, 2026

Retroperitoneal Laparoscopic Debridement and Drainage for Pancreatic Abscess
03:42

Retroperitoneal Laparoscopic Debridement and Drainage for Pancreatic Abscess

Published on: March 15, 2024

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
06:45

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis

Published on: December 18, 2010

Area of Science:

  • Critical care medicine
  • Surgical infections
  • Peritonitis management

Context:

  • Controversy exists regarding optimal surgical and antibiotic strategies for secondary peritonitis with organ failure.
  • The impact of critical care advancements, like the Surviving Sepsis Campaign, on this specific patient group is unclear.

Purpose:

  • To review current concepts in surgical and antibiotic therapy for secondary peritonitis and organ failure.
  • To assess the influence of critical care progress on patient outcomes in this population.

Summary:

  • Inadequate initial antibiotic therapy and failure to achieve source control are linked to higher mortality.
  • Planned and on-demand relaparotomies are complementary strategies, depending on intraoperative findings.
  • Treatment initiated after 2002 showed an improved prognosis, suggesting the efficacy of newer adjuvant therapies.

Impact:

  • Source control is the primary determinant of acute survival in secondary peritonitis.
  • The number of surgical revisions does not correlate with survival outcomes.
  • Recent prognostic improvements highlight the effectiveness of contemporary adjuvant therapeutic measures in high-risk surgical patients.