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Updated: Aug 2, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Topical corticosteroid therapy in psoriasis vulgaris
1Psoriasis Research Institute, Palo Alto, California 94301.
Cutis
|October 1, 1990
Summary
This review covers topical corticosteroid therapy, focusing on psoriasis treatment. It details drug classification, absorption, action, selection based on skin conditions, and side effect prevention for potent corticoids.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Topical corticosteroids are a cornerstone therapy for inflammatory skin conditions.
- Psoriasis treatment often involves topical corticosteroids, necessitating a thorough understanding of their application.
Purpose of the Study:
- To provide a comprehensive review of topical corticosteroid therapy.
- To emphasize the classification, use, and considerations for topical corticosteroids in psoriasis management.
Main Methods:
- Literature review of topical corticosteroid therapy.
- Discussion of percutaneous absorption, mechanism of action, and selection criteria.
- Analysis of equivalence concepts and side effect profiles.
Main Results:
- Classification and specific uses of topical corticosteroids in psoriasis are detailed.
- Factors influencing the choice of steroid preparations and vehicles are outlined.
- Equivalence concepts and common side effects, with prevention strategies, are reviewed.
Conclusions:
- Effective management of psoriasis with topical corticosteroids requires careful consideration of drug properties and patient-specific factors.
- Understanding absorption, action, and potential side effects is crucial for optimizing therapy and minimizing risks, especially with superpotent agents.
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