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Published on: March 2, 2011
Differential display
G C Sellar1, G J Rabiasz, B Smith
1Imperial Cancer Research Fund Medical Oncology Unit, Western General Hospital, Edinburgh, Scotland.
Abstract:
Differential display reverse transcriptase polymerase chain reaction (DDRT-PCR) is an extremely powerful method for analyzing differences in gene expression between matched tissue/cell samples. Liang and Pardee originally described the technique in 1992 in their seminal paper (1). DDRT-PCR is now firmly established as a widespread powerful and commonly used method for identifying differentially expressed genes.
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