Related Experiment Video
Updated: Jun 4, 2026

09:30
Detection of Functional Matrix Metalloproteinases by Zymography
Published on: November 8, 2010
Detection and quantitation of matrix metalloproteases by zymography
Methods in Molecular Medicine
|February 23, 2011
Abstract:
Matrix metalloproteases (MMPs) are a family of structurally and functionally related endopeptidases. They have in common a zinc ion at the active site and are released as an inactive proform (zymogen). Proteolytic activation enables MMPs to degrade components of the extracellular matrix such as collagens, fibronectin, and laminin [for review see (1-4)].
