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C Clarke1, S Davies

  • 1LICR/UCL Breast Cancer Laboratory, Department of Surgery, Royal Free and University College Medical School, London, UK.

Methods in Molecular Medicine
|February 23, 2011
PubMed

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Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.