Syngeneic murine metastasis models : b16 melanoma
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Injection of Syngeneic Murine Melanoma Cells to Determine Their Metastatic Potential in the Lungs
Published on: May 24, 2016
1LBTM, Department of Oncology, Mario Negri Institute for Pharmacological Research, Bergamo, Italy.
Methods in Molecular Medicine
|February 23, 2011
Abstract:
Animal studies are costly, time consuming, and subject to several restrictive regulations. However, the metastatic process is one of the research areas in which the in vivo studies remain most relevant (1). In fact, the in vitro studies are not fully predictive of the metastatic behavior of a tumor cell, probably because in vitro, it is difficult to reproduce the complexity of the metastatic process in itself and the interaction with the host.

