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Related Experiment Video

Updated: Jun 4, 2026

Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development

Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development

Published on: April 15, 2013

7 detecting cholesteryl ester transfer protein in plasma.

A Ritsch¹, J R Patsch

¹Department of Medicine, University of Innsbrück, Innsbrück, Austria.

Methods in Molecular Medicine

|February 23, 2011

Summary

This summary is machine-generated.

Plasma lipid transport involves two main lipoprotein groups: triglyceride-rich and cholesterol-rich. These are linked by cholesteryl ester transfer protein (CETP), a key plasma glycoprotein.

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Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation

Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation

Published on: January 28, 2021

Area of Science:

Lipid metabolism and cardiovascular science.

Background:

Plasma lipid transport involves distinct lipoprotein classes: triglyceride-rich (chylomicrons, VLDL) and cholesterol-rich (LDL, HDL).
These lipoprotein metabolisms are interconnected through lipid exchange processes.

Purpose of the Study:

To elucidate the role of cholesteryl ester transfer protein (CETP) in linking different lipoprotein metabolisms.

Main Methods:

The study focuses on the catalytic function of a specific plasma glycoprotein.

Main Results:

Cholesteryl ester transfer protein (CETP), also known as lipid transfer protein I (LTP-I), is identified as the primary catalyst for lipid exchange between lipoprotein groups.
This protein facilitates the metabolic linkage between triglyceride-rich and cholesterol-rich lipoproteins.

Conclusions:

CETP plays a crucial role in the coordinated metabolism of plasma lipoproteins.
Understanding CETP function is vital for comprehending lipid transport dynamics and potential therapeutic targets.