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Updated: Jun 4, 2026

Methods for Detecting Cough and Airway Inflammation in Mice
Published on: August 2, 2024
[Causes of chronic cough in children: an analysis of 111 cases]
Xiao-Bo Zhang1, Guang-Min Nong
1Department of Pediatrics, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Objective:
To investigate the causes of chronic cough in children.
Methods:
A prospective cohort study was performed on 111 children with chronic cough who were referred to the First Affiliated Hospital of Guangxi Medical University between December 2008 and January 2011. The causes of chronic cough were investigted.
Results:
Cough variant asthma (45 cases, 40.5%) was the most common cause of chronic cough, followed by upper airway cough syndrome (34 cases, 30.6%), postinfectious cough (19 cases, 17.1%), allergic cough (5 cases, 4.5%), Tourette's syndrome (4 cases, 3.6%), psychogenic cough (1 case, 0.9%) and endobronchial tuberculosis (1 case, 0.9%). The causes were not identified in 2 cases (1.8%). A single cause for chronic cough was noted in 60 patients (54.1%), and multiple potential causes were noted in 49 patients (44.1%), including two coexisting causes in 47 patients (42.3%) and three in 2 patients (1.8%).
Conclusions:
The top three causes of chronic cough in children are cough variant asthma, upper airway cough syndrome and postinfectious cough.
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Chronic Pharyngitis
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...