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Experimental Approaches to Study Mitochondrial Localization and Function of a Nuclear Cell Cycle Kinase, Cdk1
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Published on: February 25, 2016

Cyclin D1 inhibits mitochondrial activity in B cells

Guergana Tchakarska1, Mikel Roussel, Xavier Troussard

  • 1Biologie Moléculaire et Cellulaire de la Signalisation, EA 3919, UFR de médecine, IFR 146, Université de Caen, Caen, France.

Cancer Research
|February 24, 2011
PubMed
Summary

Cyclin D1, a cell cycle protein, inhibits mitochondrial activity by binding to the outer mitochondrial membrane. This binding disrupts energy production, suggesting a role in cell malignancy.

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