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Updated: Jun 4, 2026

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
Published on: June 8, 2022
Transcatheter valve repair/implantation
Robert J Siegel1, Huai Luo, Simon Biner
1The Heart Institute, Cedars-Sinai Medical Center, 8700 Beverly Blvd., Room 5623, Los Angeles, CA 90048, USA. siegel@cshs.org
Real-time 3D transesophageal echo (TEE) offers precise imaging for cardiac structures and guidance during structural heart interventions. This advanced technology significantly improves evaluation and monitoring of percutaneous heart valve procedures.
Area of Science:
- Cardiology
- Medical Imaging
- Interventional Cardiology
Background:
- Real-time 3D transesophageal echocardiography (TEE) is an emerging imaging modality.
- Accurate imaging of cardiac structures is crucial for interventional procedures.
- Guidance during structural heart disease interventions requires precise visualization.
Purpose of the Study:
- To describe the application of real-time 3D TEE in structural heart interventions.
- To highlight the utility of 3D TEE for procedural guidance and assessment.
- To evaluate the role of 3D TEE in aortic valve replacement and mitral valve repair.
Main Methods:
- Utilized real-time 3D transesophageal echocardiography (TEE).
- Applied 3D TEE for pre-procedural evaluation of valvular structures.
- Employed 3D TEE for online guidance and post-procedural assessment.
Main Results:
- Demonstrated accurate and precise imaging of cardiac structures.
- Showcased effective online guidance for interventional cardiac procedures.
- Confirmed successful application in percutaneous aortic valve replacement and transcatheter mitral repair using the MitraClip device.
Conclusions:
- Real-time 3D TEE is a substantial advancement in evaluating patients for percutaneous heart valve procedures.
- 3D TEE provides critical guidance and monitoring during transcatheter heart valve interventions.
- This technology enhances the precision and accuracy of structural heart disease interventions.
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