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Skew deviation after intratympanic gentamicin therapy
Diana Ng1, Mohammad Fouladvand, Anil K Lalwani
1Department of Ophthalmology, New York University School of Medicine, New York, New York, USA.
Intratympanic gentamicin for Ménière's disease can cause temporary double vision. This visual disturbance, specifically skew deviation, resolved on its own in two patients within weeks.
Area of Science:
- Otolaryngology
- Neurology
- Ophthalmology
Background:
- Intratympanic gentamicin is a common treatment for Ménière's disease, primarily targeting vertigo.
- Auditory and vestibular side effects are known, but visual disturbances are not well-documented.
Purpose of the Study:
- To report a previously undescribed visual complication of intratympanic gentamicin therapy.
- To highlight the potential for skew deviation and diplopia following this treatment.
Main Methods:
- Case report of two patients with Ménière's disease.
- Observation of visual symptoms after receiving intratympanic gentamicin injections.
Main Results:
- Both patients developed sudden onset binocular vertical diplopia.
- The diplopia was attributed to skew deviation.
- Symptoms resolved spontaneously within 6 to 8 weeks without intervention.
Conclusions:
- Sudden onset diplopia due to skew deviation is a potential, albeit rare, complication of intratympanic gentamicin.
- This visual disturbance can resolve spontaneously.
- Clinicians should counsel patients on this possible side effect.
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