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Canthaxanthin retinopathy: long-term observations
Arno Hueber1, André Rosentreter, Maria Severin
1Centre of Ophthalmology, University Hospital of Cologne, Cologne, Germany. arno.hueber@uni-koeln.de
Purpose:
To describe the long-term outcome of canthaxanthin retinopathy.
Methods:
We identified 13 patients with small golden particles near the macular region among a group of 35 patients with known consumption of canthaxanthin somewhen between 1983 and 1988. One long-term follow-up examination was possible in 5 of 13 cases after 16-24 years. The examinations included determination of visual acuity, the Amsler grid, slit lamp examination, perimetry, electro-oculography, electroretinography, optical coherence tomography and fluorescein angiography.
Results:
Complete disappearance of the golden particles took approximately 20 years. The patients in our study were asymptomatic and no functional defect related to canthaxanthin could be detected.
Conclusions:
Ingestion of canthaxanthin causes no long-term adverse effects.
