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Related Concept Videos

Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
Gastritis II: Pathophysiology01:26

Gastritis II: Pathophysiology

The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
Gastritis-I: Introduction and Types01:27

Gastritis-I: Introduction and Types

Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...

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Updated: Jun 4, 2026

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E
09:48

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E

Published on: September 26, 2019

Collagenous gastroduodenitis.

Tarun Rustagi1, Mridula Rai, John V Scholes

  • 1Department of Internal Medicine, University of Connecticut, Farmington, CT 06032, USA. trustagi@resident.uchc.edu

Journal of Clinical Gastroenterology
|February 25, 2011
PubMed
Summary
This summary is machine-generated.

Collagenous gastroduodenitis, a rare condition of subepithelial collagen deposition in the stomach and duodenum, is presented. This report details the second known case, and the first in English literature, of this isolated gastrointestinal finding.

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Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
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Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer

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Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E
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Area of Science:

  • Gastroenterology
  • Histopathology

Background:

  • Collagenous gastroduodenitis is a rare histopathologic finding.
  • It involves subepithelial collagen deposition and mucosal inflammation.
  • Most reported cases are associated with collagenous colitis.

Observation:

  • A 68-year-old woman presented with dyspepsia and mild anemia.
  • Endoscopic examination revealed nodular gastric and duodenal mucosa.
  • Histopathology confirmed collagenous gastroduodenitis.

Findings:

  • This case represents the second reported instance of collagenous gastroduodenitis.
  • It is the first reported case of isolated collagenous gastroduodenitis in the English literature.
  • The patient's presentation was without concurrent collagenous colitis.

Implications:

  • Highlights the extreme rarity of isolated collagenous gastroduodenitis.
  • Contributes to the limited case reports of this specific gastrointestinal condition.
  • May prompt consideration of collagenous gastroduodenitis in differential diagnoses for dyspepsia with specific endoscopic findings.