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Assaying Protein Kinase Activity with Radiolabeled ATP
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From the loading dock to the boardroom: a new job for Akt kinase

Sonia Feau1, Stephen P Schoenberger

  • 1Laboratory of Cellular Immunology, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA.

Immunity
|February 26, 2011
PubMed

A new report in Immunity shows that, rather than driving the metabolic changes required for proliferation, Akt controls the gene expression programs that determine whether activated CD8+ T cells differentiate into memory or effector cells.

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