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Published on: April 17, 2026
Isolated papillary muscle rupture complicating acute pancreatitis
Piercarlo Ballo1, Giuseppe Mangialavori, Irene Betti
1Department of Cardiology, S. Maria Annunziata Hospital, ASL 10, Florence, Italy. pcballo@tin.it
Abstract:
Papillary muscle rupture in the absence of coronary stenoses is a rare event. An isolated infarction of the papillary muscle is involved in most cases, but the pathogenesis is still debated. We describe an anterolateral papillary muscle rupture complicating acute pancreatitis in a patient without significant coronary stenoses and with evidence of coronary spasm. This suggests that an increased susceptibility to coronary spasm and thrombosis, triggered by an acute systemic inflammatory response, may represent a mechanism of selective papillary muscle infarction.
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