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Updated: Jun 4, 2026

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach
Published on: May 7, 2019
[Kidney transplantation in the rat: An institutional technique]
M-O Timsit1, X Ge, X Yuan
1Transplant surgery research laboratory, Division of transplant surgery, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood avenue, Boston, MA 02115, USA. marc-olivier.timsit@egp.aphp.fr
Abstract:
Kidney transplantation in rats is a classic experimental model used in transplant research. As several methods have been previously reported without definition of a gold standard, we describe herein a simple institutional technique that has been used in more than 500 procedures and taught to medical students or surgeons without previous microsurgical experience. Our step-by-step illustrated report would allow French-speaking trainees to learn how to perform kidney transplantation in rats in a reproducible manner and add this valuable tool to their research protocols.
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Kidney Transplant I: Introduction
Kidney Transplant II: Surgical Procedure

