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Updated: Jun 4, 2026

Formation of Dispersible Taohong Siwu Tablets
Published on: February 3, 2023
[Correlation of powder properties and formability of traditional Chinese medicine pellets]
Yang Huang1, Xiaobin Jia, Jing Zhu
1Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China. shoujiao.student@sina.com
Objective:
To investigate the correlation of powder properties and formability of traditional Chinese medicine pellets prepared by extrusion/spheronization.
Method:
The present effort was designed to evaluate the effects of the characters of powder on pellets formation by extrusion-spheronization, taking Danggui Buxue decoction extracts as a model drug and microcrystalline cellulose (MCC) as an ideal balling material for extrusion-spheronization.
Result:
The diameter of powder had correlation with the plane critical angle of pellets in a certain scope and the sticky coefficient of wet mass affected roundness of pellets.
Conclusion:
Properties of powder have influence on formability of traditional Chinese medicine pellets.
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