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Interactions between the COMT Val108/158Met polymorphism and maternal prenatal smoking predict aggressive behavior

Patricia A Brennan1, Constance Hammen, Patrick Sylvers

  • 1Department of Psychology, 36 Eagle Row, Emory University, Atlanta, GA 30322, USA. pbren01@emory.edu

Biological Psychology
|March 2, 2011
PubMed
Summary

Maternal prenatal smoking increased offspring aggression, but only in youth with a specific catechol O methyltransferase gene (COMT) variant. This gene-environment interaction highlights genetic influences on externalizing disorders.

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