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Related Concept Videos

Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...

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Related Experiment Video

Updated: Jun 4, 2026

An Integrated Approach for Microprotein Identification and Sequence Analysis
09:37

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

Browsing HapMap Data Using the Genome Browser.

Albert Vernon Smith

    CSH Protocols
    |March 2, 2011
    PubMed
    Summary
    This summary is machine-generated.

    The International Haplotype Map Project created a comprehensive human genome map detailing common genetic variations. This resource, including millions of single-nucleotide polymorphisms (SNPs), aids researchers in identifying genetic causes of human diseases.

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    Last Updated: Jun 4, 2026

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    Pattern-based Search of Epigenomic Data Using GeNemo
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    Pattern-based Search of Epigenomic Data Using GeNemo

    Published on: October 8, 2017

    Area of Science:

    • Human Genetics
    • Genomics
    • Bioinformatics

    Background:

    • The International Haplotype Map Project aimed to map common patterns of human genetic variation.
    • Understanding genetic variation is crucial for identifying genes associated with diseases.

    Purpose of the Study:

    • To develop a haplotype map of the human genome.
    • To accelerate the discovery of genetic factors contributing to human diseases.
    • To provide researchers with tools to explore genetic variation data.

    Main Methods:

    • Genotyping of approximately 3.9 million distinct single-nucleotide polymorphisms (SNPs).
    • Analysis of data from 270 individuals across four worldwide populations.
    • Development of a public website with data browsing and analysis tools.

    Main Results:

    • Creation of a comprehensive haplotype map of the human genome.
    • Identification of millions of common SNPs and their allele frequencies.
    • Public accessibility of genotype data through the HapMap website.

    Conclusions:

    • The HapMap project provides a valuable resource for genetic research.
    • The generated data facilitates the identification of genetic variations linked to human diseases.
    • The HapMap website serves as a central portal for accessing and analyzing human genetic variation data.