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SNP Mining from Maize 454 EST Sequences

W Brad Barbazuk1, Scott Emrich, Patrick S Schnable

  • 1Donald Danforth Plant Science Center, St. Louis, MO 63132, USA.

CSH Protocols
|March 2, 2011
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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...