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Updated: Jun 4, 2026
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Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study
Published on: April 11, 2018
Genetic analysis of cystic fibrosis airway epithelial cells
1Department of Biology, Human Gene Therapy Working Group, Universidad Nacional del Sur, Bahia Blanca, Argentina.
Methods in Molecular Medicine
|March 2, 2011
Abstract:
More than 500 different mutations have been described to date on the cystic fibrosis (CF) gene (1). The most frequent mutation is the so-called ΔF508 mutation, which accounts for 30-50%;of CF chromosomes in southern European countries and for 50-80%; of CF chromosomes in the United States, Canada, Argentina, and central and northern European countries.
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