Related Experiment Video
Updated: Jun 4, 2026
Rotating Cell Culture Systems for Human Cell Culture: Human Trophoblast Cells as a Model
Published on: January 18, 2012
Superfused Microcarrier Cultures of BeWo Choriocarcinoma Cells : A Dynamic Model for Studies of Human Trophoblast
1Department of Obstetrics and Gynecology, Chelsea and Westminister Hospital, London, UK.
The human placenta is a unique and still very poorly understood organ During gestation, it is responsible for performing most synthetic and transport functions that are necessary to ensure the normal growth and development of the fetus in utero. Subsequently, at birth it is discarded. Current understanding of the role of the placenta in maintaining fetal homeostasis is based primarily on studies using either artificially perfused term placental lobules, placental slices or explants, or isolated plasma membrane fractions (1-3). Studies with placental tissue are complicated by the presence of serial tissue layers in the maternofetal barrier, i e., syncytiotrophoblast, cytotrophoblast, and fetal endothelium, as well as by the presence of other cell types within the placental tissue, such as the Hofbauer cells or placental macrophages.
The human placenta is a unique and still very poorly understood organ During gestation, it is responsible for performing most synthetic and transport functions that are necessary to ensure the normal growth and development of the fetus in utero. Subsequently, at birth it is discarded. Current understanding of the role of the placenta in maintaining fetal homeostasis is based primarily on studies using either artificially perfused term placental lobules, placental slices or explants, or isolated plasma membrane fractions (1-3). Studies with placental tissue are complicated by the presence of serial tissue layers in the maternofetal barrier, i e., syncytiotrophoblast, cytotrophoblast, and fetal endothelium, as well as by the presence of other cell types within the placental tissue, such as the Hofbauer cells or placental macrophages.
More Related Videos
12:02Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
Published on: July 30, 2016
09:57In Vitro Assays to Evaluate the Migration, Invasion, and Proliferation of Immortalized Human First-trimester Trophoblast Cell Lines
Published on: March 5, 2019