Related Experiment Video
Updated: Jun 4, 2026

Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis
Published on: May 16, 2025
Chemical colitis from a hydrogen peroxide enema
Yagnesh Desai1, Jeffery Orledge
1Department of Emergency Medicine, University of Mississippi Medical Center, Jackson 39216, USA. ydesai@umc.edu
Hydrogen peroxide enemas can cause chemical colitis, leading to severe abdominal pain and rectal bleeding. This case highlights the risks of using household chemicals for constipation relief.
Area of Science:
- Gastroenterology
- Toxicology
Background:
- Constipation is a frequent emergency department complaint.
- Patients often self-treat constipation with various remedies.
- Enemas are a common method for constipation relief.
Observation:
- A 43-year-old male with chronic constipation used a hydrogen peroxide and sodium phosphate enema.
- He developed severe abdominal pain and hematochezia shortly after administration.
- Imaging revealed moderate to severe colitis involving the rectum and colon.
Findings:
- The patient's symptoms of abdominal pain and hematochezia resolved.
- He was discharged the following day without further complications.
- Chemical colitis was diagnosed secondary to the hydrogen peroxide enema.
Implications:
- This case underscores the potential dangers of using hydrogen peroxide enemas.
- Healthcare providers should counsel patients on safe constipation management.
- Alternative, evidence-based treatments for constipation are recommended.
Related Concept Videos
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease II: Ulcerative Colitis
Drugs for Treatment of Ulcerative Colitis in IBD
Prevention of Further Absorption of Poison
Inflammatory Bowel Disease I: Introduction
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
