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Updated: Jun 4, 2026

Dissection of the Endolymphatic Sac from Mice
Published on: March 29, 2021
Visualization and assessment of saccular duct and endolymphatic sinus
Hideo Yamane1, Masahiro Takayama, Kishiko Sunami
1Department of Otorhinolaryngology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abenoku, Osaka, Japan. ent-yamane@med.osaka-cu.ac.jp
Conclusion:
The saccular duct and endolymphatic sinus run in the bony groove, before reaching the orifice of the vestibular aqueduct. We first clinically visualized this sulciform groove using three-dimensional (3D) cone beam CT images. This strategy can be useful to assess the condition of the saccular duct and endolymphatic sinus concerning the longitudinal flow system of endolymph.
Objective:
To assess the saccular duct and endolymphatic sinus in the endolymphatic system in order to advance clinical studies on inner ear dysfunction.
Methods:
The sulciform groove of the saccular duct and endolymphatic sinus of human subjects was analyzed by cone beam CT and compared with that of a cadaver.
Results:
We could obtain reconstructed 3D CT images of the sulciform groove of the saccular duct and endolymphatic sinus using several CT window levels.
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