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Published on: April 22, 2010
Hematological and serum biochemical indices in healthy bonnet macaques (Macaca radiata)
Peter J Pierre1, Marlon K Sequeira, Christopher A Corcoran
1Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Background:
Blood reference values for bonnet macaques (Macaca radiata) are limited. The goal of this study was to determine reference ranges for hematological and serum biochemical indices in healthy, socially housed bonnet macaques for males and females over a range of ages.
Methods:
Blood hematological and serum biochemical values were obtained from 50 healthy bonnet macaques of both sexes and aged 10-234 months.
Results:
Age and sex differences were present in a number of measures. Globulins, total protein, and creatinine (CREAT) values were highest among older subjects, while alkaline phophatase, albumin, and phosphorus values were higher in juveniles. Sex differences were present in concentrations of red blood cells and CREAT, with higher values in males.
Conclusion:
The blood parameter data reported here as age-specific reference values for laboratory-housed, healthy bonnet macaques may be used to inform clinical care and laboratory primate research.
