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Updated: Jun 4, 2026

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
Published on: April 9, 2014
Abstract:
Definite or suspected occupational exposure of healthcare workers to human immunodeficiency virus (HIV) infection is a medical emergency. Post-exposure prophylaxis (PEP) with antiretroviral drugs is widely available following such exposure, aiming to prevent HIV infection. PEP following non-occupational exposure (nPEP) is also increasingly being provided. The term PEPSE (PEP following sexual exposure) is also commonly used, recognising that most non-occupational exposure is sexual. Here we discuss the evidence supporting the use of PEP and nPEP and advice in current guidelines.
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