Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 4, 2026

Determination of the Excitation and Coupling Rates Between Light Emitters and Surface Plasmon Polaritons
07:39

Determination of the Excitation and Coupling Rates Between Light Emitters and Surface Plasmon Polaritons

Published on: July 21, 2018

White-light spectral interferometry for surface plasmon resonance sensing applications.

Siu Pang Ng1, Chi Man Lawrence Wu, Shu Yuen Wu

  • 1Department of Physics and Materials Science, City University of Hong Kong, Hong Kong.

Optics Express
|March 4, 2011
PubMed
Summary

A new surface plasmon resonance (SPR) sensor uses white-light interferometry for enhanced sensitivity and a wider dynamic range. This novel approach improves upon laser-based methods for practical sensing applications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hydrogel bead-based isothermal detection (BEAD-ID) for assessing the activity of DNA-modifying enzymes.

iScience·2024
Same author

Automated Uniform Spheroid Generation Platform for High Throughput Drug Screening Process.

Biosensors·2024
Same author

Technological Advances in Multiscale Analysis of Single Cells in Biomedicine.

Advanced biosystems·2020
Same author

Extracellular Histones Induced Eryptotic Death in Human Erythrocytes.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology·2019
Same author

Recent Advances in Surface Plasmon Resonance Imaging Sensors.

Sensors (Basel, Switzerland)·2019
Same author

Real-time multi-channel SPR sensing based on DMD-enabled angular interrogation.

Optics express·2018

Area of Science:

  • Optics and Photonics
  • Analytical Chemistry
  • Biomedical Engineering

Background:

  • Surface Plasmon Resonance (SPR) is a label-free optical sensing technique.
  • Existing laser-based SPR sensors face limitations in dynamic range and sensitivity.
  • Phase detection in SPR offers high sensitivity but requires complex setups.

Purpose of the Study:

  • To present a novel differential phase detecting SPR sensor.
  • To utilize white-light spectral interferometry for SPR excitation and phase measurement.
  • To enhance sensitivity and expand the dynamic range of SPR measurements.

Main Methods:

  • Employing a white-light source for SPR excitation.
  • Measuring SPR phase changes at an optimized coupling wavelength.

More Related Videos

Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations
06:19

Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations

Published on: June 23, 2022

Related Experiment Videos

Last Updated: Jun 4, 2026

Determination of the Excitation and Coupling Rates Between Light Emitters and Surface Plasmon Polaritons
07:39

Determination of the Excitation and Coupling Rates Between Light Emitters and Surface Plasmon Polaritons

Published on: July 21, 2018

Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations
06:19

Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations

Published on: June 23, 2022

  • Utilizing a fixed angle of incidence across the visible spectrum.
  • Main Results:

    • Achieved a detection limit of 2.6×10⁻⁷ Refractive Index Unit (RIU).
    • Demonstrated a refractive index measurement range of 10⁻² RIU.
    • Showcased optimal sensitivity and extended dynamic range compared to laser-based schemes.

    Conclusions:

    • The proposed white-light SPR sensor offers superior performance over existing laser-based methods.
    • The enhanced dynamic range makes the system highly suitable for practical SPR sensing applications.
    • This novel approach provides a robust platform for sensitive and wide-range refractive index detection.