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Detection of Intracellular Gene Expression in Live Cells of Murine, Human and Porcine Origin Using Fluorescence-labeled Nanoparticles
Published on: November 13, 2015
Encapsulated enhanced green fluorescence protein in silica nanoparticle for cellular imaging
Zhengwei Cai1, Zhangmei Ye, Xiaowei Yang
1Institute of Nanochemistry and Nanobiology, Shanghai University, Shanghai, 200444, China.
Nanoscale
|March 4, 2011
Abstract:
The enhanced green fluorescence protein (EGFP) is efficiently encapsulated in silica nanoparticle by multiple covalent bonds. The silica encapsulation greatly increases EGFP's fluorescence intensity and stabilities against protease, denaturant and heat, making it a potential fluorescence probe for cellular imaging.

