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Updated: Jun 4, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Destructive granulomatous reaction to polyacrylamide lip injection: solution for a complex case
G Colombo1, P Caregnato, R Stifanese
1Center for Plastic, Reconstructive, and Esthetic Surgery and Dermatology, Via Antica Romana di Quinto 119, 16161 Genoa, Italy.
Abstract:
The inappropriate and careless use of permanent fillers causes severe and undesirable side effects, as shown by a number of reported clinical cases. The dramatic case described in this report strongly demonstrates that inadequate knowledge of implanted materials has a heavy impact on the patient's health and his or her desired results. Both are aspects that sometimes prove very difficult to ameliorate. Moreover, the solution for the reported case clearly demonstrates that only the careful application of fine surgery can solve these problems. This is true also for cases initially believed to be hopeless.
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