Microencapsulation of enzymes, cells, and genetically engineered microorganisms.

Area of Science:

• Biomaterials Science
• Biotechnology
• Regenerative Medicine

Background:

• The concept of microencapsulating biologically active materials into artificial cells dates back to 1964.
• Extensive development in artificial cell technology has occurred over the last decade.
• Recent advancements focus on specific therapeutic applications.

Purpose of the Study:

• To highlight recent advancements in artificial cell technology.
• To showcase applications in blood substitutes, enzyme therapy, and cell therapy.
• To provide examples of developed artificial cell systems.

Main Methods:

• Microencapsulation techniques for creating artificial cells.
• Development of artificial cells for specific biomedical applications.
• Focus on three key areas: blood substitutes, enzyme therapy, and cell therapy.

Main Results:

• Demonstrated feasibility of artificial cells for various therapeutic uses.
• Progress in developing artificial cells for blood substitutes.
• Advancements in enzyme and cell therapy using artificial cell technology.

Conclusions:

• Artificial cell technology has matured significantly since its inception.
• The technology holds promise for diverse therapeutic applications, including blood substitutes, enzyme, and cell therapies.
• Further development is ongoing for specialized applications.