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Updated: Jun 3, 2026

Isolation of Epithelial Cells from Human Dental Follicle
Published on: November 5, 2021
[Keratocysts (or keratocystic epithelial odontogenic tumors)]
B Ruhin-Poncet1, A Picard, N Martin-Duverneuil
1Service de stomatologie et chirurgie maxillofaciale, hôpital de la Pitié-Salpêtrière, université Pierre-et-Marie-Curie Paris 6, 47-83, boulevard de l'Hôpital, 75013 Paris cedex 13, France. blandine.ruhin@psl.aphp.fr
Abstract:
The aim of this study was to describe the management of keratocysts based on our own experience and on a large literature review. Keratocysts are benign odontogenic epithelial tumors. The main aspects of this lesion are described (definition, epidemiology, clinic, radiology, histology, treatment, and prognosis). In small intra-osseous tumors, surgical procedure must be as conservative as possible, most often enucleation. In large tumors with destruction of the cortical bone, or with destruction of coronoid process or notch, extensive resection can be indicated, with sometimes a transfacial approach for an accurate control, especially in soft tissues. Strict follow-up is mandatory because of the high risk of recurrence.
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